Hypertonic Saline vs Normal Saline in Bronchiolitis

aprile 19, 2016adminArticoli Scientifici

3% Hypertonic Saline Versus Normal Saline in Inpatient Bronchiolitis: A Randomized Controlled Trial

BACKGROUND AND OBJECTIVES: We aimed to investigate the effect of nebulized 3% Hypertonic Saline compared with nebulized normal saline (NS) on length of stay (LOS) in infants hospitalized with bronchiolitis. Bronchiolitis, the most common reason for hospitalization in children younger than 1 year in the United States, has no proven therapies effective beyond supportive care.

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Colonization by respiratory pathogens

aprile 19, 2016adminArticoli Scientifici

Dynamics of nasopharyngeal colonization by potential respiratory pathogens

Studies have shown that colonization of the nasopharynx by potential respiratory pathogens Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis is established early in childhood, although rates vary greatly according to locality, sampling frequency, individual and social factors. Factors influencing colonization and elimination are not as yet fully understood, but adhesion to mucosal receptors and immune responses are implicated in addition to bacterial properties and colonization resistance dynamics.

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